This is a personal-budget science computing rig.
The 1080ti just arrived and works ok. This is my 3rd AMD desktop (K6-233 served me 1996-2004, Athlon64 2004-2017).
Computer is matched with three K272HUL (on sale at Newegg) 2K monitors for Nvidia Surround.
Roughly half my money for this build went to Microcenter, third to Nvidia store, and sixth to Newegg. Too bad Nvidia charges sales tax.
The Ryzen 1800X got tested ok to 4250 MHz. TridentZ runs at 3200-16. It only ran at 2933 with 1700X, so memory speed does depend on the CPU (data fabric clock in Ryzen); Crosshair VI board is with original BIOS 0702.
H60 cooler helps lower the CPU temperature by 2-3°C compared to air cooler. Crosshair VI has so much plastic on it that it prevents normal (roof) installation of the water cooler radiator in a normal ATX mid tower case. I had to mount the radiator on the front of the case. Now the case had to be modded to fit the radiator.
Airflow velocity and pressure calculation done with Epanet2 hydraulic analysis tool.
Ryzen and Nvidia GTX 1080 ti power consumption does not exceed 453W so the 850W power supply was a bit too much. This power includes 3 displays (Acer 272HUL) in Nvidia Surround for Ghost Recon Wildlands, measured with CyberPower 1350PFCLCD at the power cables.
1080ti temperature runs ~75°C inside, measured with SeekThermal camera.
Update: Started with a $2000 budget but memory upgrade from 16 to 32GB and the second 1080ti pushed it a bit over 2K; Now half of the total budget went to Nvidia, the rest is mostly Microcenter. CPU runs at 3.97 GHz, memory at 3200-16 speed. Using BIOS 9945 but planning to update to the just released 3101. SLI works well both in Win10 ver.1709 and in Ubuntu ver.1704.