Rebuilt an existing machine into a Define R5 Blackout to fit a new desk. The R5 is a very nice case to work in. A pleasant surprise moving from a CM Storm Trooper.
A great cooler all around. Uses Noctua's fantastic Secufirm 2 mounting system, making installing or removing the cooler a breeze. Manages to stay nearly silent while keeping my overclocked i7-6800k at a mere 60 degrees (celcius). 10/10 would recommend.
Honestly this board is alright, but not fantastic. The included USB Type-C back panel connector is nice, and the LEDs look alright. However, despite all of the fan connectors being 4-pin, only CPUFAN1 uses PWM speed control (the others all use voltage control). And as of March 2017 (this may have changed depending on when you're reading this) the LED control software is abysmally bad. It's impossible to control the LEDs without installing the "MSI Gaming App" which includes a whole lot of redundant features (mouse DPI settings, keyboard macros, etc.); there's also no way to control the LEDs (or turn them off) on a non-windows system, as basic LED settings don't persist through reboots.
Maybe with time MSI can fix some of the issues with the gaming app (just give us a standalone LED controller please), at which point this board might be bit of a better purchase.
A fantastic case all around, and very very quiet (even when stress testing). Cable management is easy using the included velcro straps on the back of the motherboard tray. Has a lot of storage potential for a mid-tower case. Bottom dust filter pulls out entirely from the front so you don't have to reach around the back to clean off the PSU filter. Only downside is that there's no dust filter for the top panel if you're planning to install exhaust fans up there.
I don't really know how much needs to be said here. They're quiet, they move a lot of air, and (assuming you can pick up an LTT edition) they don't look all that bad.