Looking for data access speed and expandability... OS/system is on the 1TB Samsung 950 Pro and fully cached using ASUS RAMDISK. All user docs, music, application installs, and data storage are on the Intel 750's (RAID0, plugged into PCIE NVMe adaptor cards and piped through m.2 via the ASUS HyperKit (M.2 to Mini SAS HD adapter) for a screaming 32 GB/s transfer speed. (https://www.asus.com/us/Motherboard-Accessories/Hyper_Kit/) Corsair H100 LC now installed and a new local backup (8TB SATA6 RAID5 Seagate Ironwolf Pro's (X4)), duped in Carbonite. Overclocked at 14% and not even a tick on temp or glitching. Thinking about GPU LC and updating the mobo/cpu...hmmmmm.
No performance issues so far...setting this up on the ROG Strix x99 was a pain. Needed two additional PCIeNVM cards tapped into the ASUS HyperKit (M.2 to Mini SAS HD adapter to support 2.5-inch NVMe SSDs): https://www.asus.com/us/Motherboard-Accessories/Hyper_Kit for 32 Gb/s.